Addison's disease

Addison's disease
a syndrome resulting from inadequate secretion of corticosteroid hormones due to the progressive destruction of the adrenal cortex. It is characterized by progressive deterioration with hypotension and collapse due to severe dehydration, salt loss, and hypoglycaemia; dark pigmentation of the skin may occur. Formerly tuberculosis was a common cause, but the condition is now more likely to be due to autoimmune destruction of the adrenal cortices (see autoimmune disease). Treatment is with hydrocortisone and fludrocortisone. [Addison]

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  • Addison's disease — Classification and external resources ICD 10 E27.1 E27.2 ICD 9 …   Wikipedia

  • Addison's disease — n a destructive disease marked by deficient adrenocortical secretion and characterized by extreme weakness, loss of weight, low blood pressure, gastrointestinal disturbances, and brownish pigmentation of the skin and mucous membranes * * * a… …   Medical dictionary

  • Addison's disease — Ad di*son s dis*ease [Named from Thomas Addison, M. D., of London, who first described it.] (Med.) A morbid condition causing a peculiar brownish discoloration of the skin, and thought, at one time, to be due to disease of the suprarenal capsules …   The Collaborative International Dictionary of English

  • Addison's disease — [ad′i sənz] n. [after T. Addison (1793 1860), Eng physician who identified it] a disease caused by failure of the adrenal glands: it is characterized by anemia, weakness, low blood pressure, and brownish discoloration of the skin …   English World dictionary

  • Addison's disease — noun Etymology: Thomas Addison died 1860 English physician Date: circa 1856 a destructive disease marked by deficient adrenocortical secretion and characterized by extreme weakness, loss of weight, low blood pressure, gastrointestinal… …   New Collegiate Dictionary

  • Addison's disease — Pathol. a disease characterized by asthenia, low blood pressure, and a brownish coloration of the skin, due to decreased secretion of cortisol from the adrenal cortex, resulting in hypoadrenalism. [1855 60; named after T. ADDISON, who described… …   Universalium

  • Addison-Schilder disease — Ad·di·son Schil·der disease (adґĭ sən shilґdər) [T. Addison; Paul Ferdinand Schilder, Austrian born neurologist in the United States, 1886–1940] adrenoleukodystrophy …   Medical dictionary

  • Addison's disease — noun a disease characterized by progressive anaemia and bronze discoloration of the skin, caused by inadequate secretion of hormones by the adrenal cortex. Derivatives Addisonian ˌadɪ səʊnɪən adjective Origin C19: named after the English… …   English new terms dictionary

  • Addison's disease — Ad′dison s disease n. pat diminished function of the adrenal glands, resulting in low blood pressure, weight loss, anxiety, darkened skin, and other disturbances • Etymology: 1855–60; after T. Addison, who described it …   From formal English to slang

  • Addison's disease — /ˈædəsənz dəziz/ (say aduhsuhnz duhzeez) noun a disease characterised by asthenia, low blood pressure, and a brownish colouration of the skin, due to progressive destruction of the suprarenal cortex. {named after T Addison, 1793–1860, English… …  

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